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. Author manuscript; available in PMC: 2011 Jun 25.
Published in final edited form as: Mol Cell. 2010 Jun 10;38(6):853–863. doi: 10.1016/j.molcel.2010.05.011

Figure 6. The MLL-AF9 fusion protein needs wild type MLL1, PAF1 and DNA binding for recruitment to HoxA9.

Figure 6

(A) Legend for the ChIP experiments in B-J. Blue line= HA ChIP in cells transfected with an empty vector, Red line= HA ChIP in cells transfected with the constructs indicated and Grey dots = the binding pattern of fh-MLL-AF9 in Mll1−/− + MLL cells for comparison. (B) – (J) α-HA ChIP across HoxA9 for the constructs and in the specific cell lines as indicated. ChIP results shown are typical for at least three independent experiments. Error bars represent standard deviation of three separate PCR reactions. See also Figure S6.