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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Gastroenterology. 2010 Mar 17;139(1):194–203.e1. doi: 10.1053/j.gastro.2010.03.035

Figure 2.

Figure 2

CDX2 promoter methylation status and mRNA expression in esophageal squamous cell lines. (2A) acid, bile salts, and acidified bile salts do not change CDX2 promoter methylation status in any of the cell lines. C, untreated control cells; A, acidic medium; B, bile salt medium; A&B, acidified bile salt medium, (2B) DAC demethylates the CDX2 promoter in all cell lines. (2C) Demethylation of the CDX2 promoter alone did not induce mRNA expression in any cell line. U, unmethylated allele; M, methylated allele.