Figure 4.

Acid and bile salts increase activity of the human CDX2 promoter construct in NES-B3T and NES-B10T cells, but not in NES-G2T and NES-G4T cells. The bar graphs depict the mean + SEM of at least 3 individual experiments. (***, p<0.001 compared with non-treated controls) pGL-3-CDX2, cells transfected with plasmid containing the CDX2 promoter construct attached to a luciferase reporter (-562 bp); pGL-3, cells transfected with pGL-3 plasmid vector lacking the CDX2 promoter; RLU, relative light units.