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Acid and bile salts increase DNA binding of p50, but not p65 to the CDX2 promoter in NES-B3T and NES-B10T cell. Panels show representative experiments of ChIP assays for p50 and p65. Note that exposure to acid, bile salts, or acidified bile salts markedly increases binding by of p50, but not p65, to the CDX-2 promoter. C, untreated control cells; A, acid exposure; B, bile salt exposure; A&B, acidified bile salt exposure; M, marker.
