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. Author manuscript; available in PMC: 2011 Aug 15.
Published in final edited form as: Exp Cell Res. 2010 May 13;316(14):2260–2277. doi: 10.1016/j.yexcr.2010.05.006

Figure 11.

Figure 11

Filopodia of hippocampal neurons transfected with the SI mutant (lacking the HS GAG-chain attachment sites) are less stable than those of neurons transfected with wild-type TM-agrin. The lifetimes of filopodia along axons were assayed in one-hour-long phase contrast time-lapse sequences of transfected neurons (n = 8 neurons for each condition). The graph shows the percentage of very stable (lifetime at least 60 min) and very labile (lifetime ≤ 1.5 min) filopodia for wild-type TM-agrin and each of the GAG-chain mutants. The asterisk indicates a value significantly different from that of wild-type TM agrin.