Fig. 5.
A. Diagram of native haplotype expression vector constructs. Differences from HapA are shown in red. B. Luciferase activity values (adjusted for Renilla luciferase activity and normalized to HapA) for native haplotypes (n = 11 wells). Bars represent standard deviation. All data is normalized to Renilla luciferase activity and adjusted relative to HapA expression (1). *p = 6.2 × 10−6 for HapB vs HapA, **p = 0.017 for HapC vs HapA. C. A polymorphism in the promoter of FGFBP1 inhibits up-regulation of luciferase reporter gene expression (adjusted for Renilla luciferase activity) by testosterone. Bars represent standard error (n = 6 wells). All data is normalized to Renilla luciferase activity and adjusted relative to HapA expression without testosterone (1). *p = 0.00087; with versus without testosterone, **p = 0.0098; with versus without testosterone.