Table 2.

Potential transcription factor binding sites for sequences containing polymorphisms. Those relevant to bone homeostasis and therefore tested in vitro are shown in bold. No relevant sites were predicted for the two other polymorphisms tested (rs2245964 and rs16892645).

SNP	Location	Allele	Construct	Promo Transcription Factor Prediction	PATCH Transcription Factor Prediction	TFsearch Transcription Factor Prediction
rs12503796	promoter	G	HapA HapC	RXRα	H4TF-2	RunX1
		T	HapB	AR, TFII-I	GR, T3Rα, T3Rβ1, T3Rβ2, RARα1, RXRβ	none