Table 4. Genes up-regulated in Trrap-deficient cells at mitosis.
| Accession no. | Gene description | Ratio |
|---|---|---|
| Cell adhesion/ECM | ||
| AI851778 | connective tissue growth factor | 2.1 |
| AI841659 | matrix metalloproteinase 13 | 2.0 |
| AI448993 | procollagen, type XVIII, alpha 1 | 6.3 |
| AI854113* | syndecan 2 | 2.3 |
| Cell cycle | ||
| AI852430 | peripheral myelin protein, 22 kDa | 2.1 |
| Cell growth/maintenance | ||
| AI842277 | insulin-like growth factor binding protein 3 | 2.3 |
| Cell proliferation/differentiation | ||
| AI843746 | fibroblast growth factor inducible 14 | 2.5 |
| Cytoskeleton/MBP | ||
| AI851494 | kinesin heavy chain member 2 | 2.1 |
| AI853411 | microtubule-associated protein 7 | 2.1 |
| AI854333 | tropomyosin 1, alpha | 2.1 |
| DNA repair | ||
| AI848686 | damage specific DNA binding protein 1 (127 kDa) | 2.3 |
| Metabolism | ||
| AI846372 | asparagine synthetase | 2.3 |
| AI842131 | ATP synthase, H+ transport., mitoch. F0 complex, subunit c | 2.0 |
| AI836445 | stearoyl-Coenzyme A desaturase 2 | 2.3 |
| AI852717 | succinate-CoA ligase, GDP-forming, alpha subunit | 2.4 |
| Protein biosynthes./degradation | ||
| AI851255 | cathepsin B | 2.1 |
| AI836333 | nitrilase 1 | 2.0 |
| AI845068 | proteasome (prosome, macropain) 26S subunit, ATPase 2 | 2.0 |
| AI851441 | proteasome (prosome, macropain) subunit, alpha type 4 | 2.1 |
| AI844521 | proteasome (prosome, macropain) subunit, alpha type 6 | 2.7 |
| Protein transport/folding | ||
| AI854749 | chaperonin subunit 3 (gamma) | 2.4 |
| AI851468* | coatomer protein complex, subunit gamma 2 | 2.2 |
| AI846861 | N-ethylmaleimide sensitive fusion protein | 2.1 |
| AI851315 | SEC61, alpha subunit 2 (S. cerevisiae) | 2.0 |
| RNA binding/processing | ||
| AI851199* | non-POU-domain-containing, octamer-binding protein | 3.8 |
| AI854330 | ribonuclease P2 | 2.4 |
| Signaling | ||
| AI844216 | abl-interactor 1 | 2.0 |
| AI853544 | guanine nucleotide releasing factor 2 | 2.7 |
| AI850105 | leukemia-associated gene | 2.1 |
| AI465474 | oncostatin receptor | 2.2 |
| AI854805 | raf-related oncogene | 2.3 |
| AI847155 | ribosomal protein S6 kinase, 90 kDa, polypeptide 4 | 2.4 |
| AI853288 | Wnt1 responsive Cdc42 homolog | 2.2 |
| Transcription | ||
| AI852906 | circadian locomoter output cycles kaput | 2.3 |
| Transport systems | ||
| AI842352 | centrin 2 | 2.5 |
| AI842091 | trans-golgi network protein 2 | 2.4 |
| Unknown function | ||
| AI846269 | 5-azacytidine induced gene 2 | 2.2 |
| AI849996 | latexin | 3.0 |
| AI850263 | lysosomal membrane glycoprotein 2 | 2.0 |
| AI854112 | retinoid-inducible serine caroboxypetidase | 2.5 |
| AI852294 | REV1-like (S. cerevisiae) | 2.8 |
| AI851503 | tumor differentially expressed 1 | 2.6 |
Transcripts marked by asterisk were also analyzed by northern blotting.