Skip to main content
. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Transplant Rev (Orlando). 2010 Jun 11;24(3):147–159. doi: 10.1016/j.trre.2010.04.002

Figure 2. AdapIve (Inducible) CD4+ CD25+ Treg Cells.

Figure 2

Murine adaptive CD4+ CD25+ Treg's can be derived in vitro through treatment of peripheral CD4+ CD25+ Treg's with TCR, anti CD28 antibodies and TGF-β. Human adaptive CD4+ CD25+ Treg's can be induced in the absence of TGF-β. Both murine and human adaptive Treg's express Foxp3 are capable to down rgulate allergic lungh inflammation and suppress in vitro induced antigen and mitogen driven T cell proliferation.