Fig 3.

IgE mediates cytokine modulation via an FcγR from dendritic cells. APC from RAG1−/− spleens and LN were sensitized with or without 5 ug/ml anti-DNP IgE on DNP-HSA coated plates and stimulated with LPS and for some samples increasing amounts of soluble 2.4G2. After 24 hours incubation, supernatant was collected and IL-12 p70 was measured by ELISA. Data are reported as mean ± SEM and representative of 3 experiments where *** P<0.0003 and ns P=0.0594.