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. Author manuscript; available in PMC: 2010 Jul 13.
Published in final edited form as: Biochemistry. 2008 Mar 27;47(16):4770–4779. doi: 10.1021/bi7023354

Table 4.

Reaction of rHDL Particles of Different Size with LCAT

rHDL
particle
size (nm)		 app Vmax [pmol of
CE h−1
(µg of LCAT)−1]a 		app Km
(µM apoA-I)a 		app Vmax/
app Km
7.8 22.30 ± 0.41 0.786 ± 0.027 28.37 ± 0.75
8.4 23.01 ± 4.02 0.515 ±0.153 44.68 ± 4.75
9.6 23.36 ± 5.06 0.275 ± 0.084 84.95 ± 8.64
12.2 16.26 ± 0.34 0.037 ± 0.004 439.46 ± 50.01
17.0 16.10 ± 1.91 0.040 ± 0.010 402.50 ± 19.81
a

The apparent kinetic parameters are the mean ± SD from three independent LCAT assays.