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. 2010 Mar 18;182(1):83–91. doi: 10.1164/rccm.201001-0005OC

Figure 4.

Figure 4.

PIK3CA and SOX2 copy number was analyzed as before, this time in sequential biopsies from three patients (002, 017, 026). (A–C) Results represent the mean ± SD of duplicate experiments for the two genes and three to five reference autosomal markers. In the case of Patient 017 (C) there was no significant increase in relative copy number in the later biopsy; however (D) there was an absolute gain in copy of both loci (PIK3CA = green; SOX2 = yellow) on the basis of fluorescence in situ hybridization experiments on the same biopsies.