Table 1. Baseline participant characteristics* stratified by serum albumin categories, ARIC, 1987-89.
| Quintile† Range (g/L) N |
Q1 20-36 2908 |
Q2 37-38 4128 |
Q3 39 2407 |
Q4 40 3703 |
Q5 41-51 2154 |
p-values |
|---|---|---|---|---|---|---|
| Age, years (SD) | 54.6 (5.8) | 54.4 (5.9) | 54.2 (5.8) | 53.9 (5.6) | 53.6 (5.7) | <0.0001 |
| Male, n (%) | 928 (31.9) | 1727 (41.8) | 1122 (46.6) | 1020 (49.3) | 2110 (55.7) | <0.0001 |
| African Americans, n (%) | 1137 (39.1) | 1106 (26.8) | 553 (23.0) | 469 (22.7) | 823 (21.7) | <0.0001 |
| HRT Use‡, n (%) | 473 (23.9) | 489 (20.4) | 209 (16.3) | 163 (15.5) | 202 (12.1) | <0.0001 |
| BMI, kg/m2 (SD) | 29.3 (6.6) | 27.9 (5.4) | 27.2 (4.8) | 27.1 (4.7) | 26.7 (4.3) | <0.0001 |
| Prevalent Diabetes, n (%) | 361 (12.5) | 289 (7.0) | 146 (6.1) | 142 (6.9) | 190 (5.0) | <0.0001 |
| History of Cancer, n (%) | 175 (1.15) | 226 (1.48) | 123 (0.81) | 112 (0.73) | 211 (1.38) | 0.53 |
| eGFRcreat (ml/min per 1.73 m2) | 97.3 (17.3) | 96.1 (14.8) | 95.3 (14.8) | 95.5 (14.5) | 95.3 (14.4) | <0.0001 |
| Factor VIII, % (SD) | 146 (48) | 132 (38) | 128 (36) | 127 (35) | 124 (35) | <0.0001 |
| aPTT, seconds (SD) | 28.9 (3.2) | 29.0 (3.0) | 29.1 (2.9) | 29.1 (2.9) | 29.2 (3.0) | 0.0003 |
| Fibrinogen, μmol/L (SD) | 9.7 (2.4) | 9.0 (1.8) | 8.7 (1.8) | 8.6-1.7) | 8.5 (1.6) | <0.0001 |
*
Values are mean (SD) or n (%)
†
Quintiles are approximate due to rounding of serum albumin measurements.
‡
Women only
Abbreviations: aPTT, activated partial thromboplastin time; ARIC, Atherosclerosis Risk in Communities; BMI, body mass index; eGFR, estimated glomerular filtration rate; HRT, hormone replacement therapy; Q, quintile