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. Author manuscript; available in PMC: 2010 Jul 13.
Published in final edited form as: Genes Chromosomes Cancer. 2008 Oct;47(10):853–859. doi: 10.1002/gcc.20589

TABLE 1.

Clinical and Pathologic Findings in BRAF mutated GIST patients

Age/Sex Primary
Tumor Size (cm)
Primary
Tumor Site
MF/50
HPF
Stage at
presentation
CD117 PTEN P16 LFU/mo
1a 52/F 10 SB 90 Periton Mets P P N DOD/18
2 55/F 10 SB 5 Primary P NA NA NED/9
3 49/F 9 SB 50 Primary P P P NED/13
4b 66/M 20 Stomach 68 Primary N N N NED/32

F, female; M, male; cm, centimeters; SB, small bowel; periton mets, peritoneal metastases; MF, mitotic figures; HPF, high power fields; P, positive; N, negative; DOD, dead of disease; NED, no evidence of disease; AWD, alive with disease; NA, not available, LFU, last follow-up; mo, months.

a

Genotyping on normal tissue as well.

b

Imatinib resistant GIST.