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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Psychopharmacology (Berl). 2009 Jun 10;206(1):61–71. doi: 10.1007/s00213-009-1579-3

Figure 1.

Figure 1

Behavior during 2-h self-administration sessions in rats with adult-onset and adolescent-onset cocaine or saline experience. Values are the mean ± SEM number of active and inactive lever responses averaged over all sessions under the FR5 contingency (top panel) and infusions earned for each of 18 self-administration sessions (bottom panel). Rats either contingently self-administered cocaine (SA cocaine) or non-contingently received cocaine (passive cocaine) or saline (passive saline) in a yoked manner. * p≤0.001 compared to the passive cocaine and saline groups and to the inactive lever.