Table 1.

Reaction of Carboxylic Acids with Arynes^a

entry	acid	product	% yieldb
1			77
2c	1		50
3			72
4			68
5			58
6			62
7			44
8			80
9d	17		71
10			22

^aReaction conditions: 0.25 mmol of acid, 1.5 equiv of benzyne precursor and 4.0 equiv of CsF in 15 mL of THF were heated in a closed vial at 125 °C for 24 h.

^bIsolated yield.

^c3.0 Equiv of benzyne precursor, 6.0 equiv of CsF and 5 mL of DME were used.

^d3-Methoxy-2-(trimethylsilyl)phenyl triflate was used as the aryne precursor.