Table 1.
Clinical and radiological data on nine children with Langerhans’ cell histiocytosis (LCH) of the spine with obvious soft tissue extension
| Case | Sex | Age at diagnosis (years) | Site of spine lesions | Pain site | Pain time | Neurological symptoms | Vertebral collapse | Site of extension | Treatment | Follow-up (months) | Clinical results |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 8.5 | T3 | Back | 1 month | Increased KJ, ankle clonus | Vertebra plana | Circumferential | Chemotherapy | 48 | Normal |
| 2 | M | 10 | T12 | Back | 10 month | Radicular pain, ankle clonus, increased KJ, Oppenheim sign (+) | Vertebra plana | Circumferential | Chemotherapy | 44 | Normal |
| 3 | M | 7 | C5 | Neck | 40 days | Radicular pain (right arm) | Lateral wedging | Paravertebral-unilateral | Chemotherapy | 40 | Normal |
| 4 | M | 4.3 | S1 | Lower back | 1 month | Radicular pain (right leg) | Lateral wedging | Paravertebral-unilateral | Chemotherapy | 37 | Normal |
| 5 | M | 3.9 | C2 | Neck | 1 month | – | No | Posterior to lamima | Chemotherapy | 28 | Normal |
| 6 | F | 9.8 | T7 | Back | 6 months | Paraplegia (Frankel B) | Anterior wedging | Circumferential | Chemotherapy+surgery | 26 | Mild kyphosis |
| 7 | M | 13 | T7 | Back | 10 days | Weakness of the lower extremities (4/5) | Lateral wedging | Paravertebral-unilateral | Chemotherapy | 18 | Normal |
| 8 | M | 5.7 | T4 | Back | 1 month | Paraplegia (Frankel C) | Vertebra plana | Spinal canal | Chemotherapy | 18 | Normal |
| 9 | M | 7 | L3 | Lower back | 1 month | Weakness of the left lower extremity (4/5) | Lateral wedging | Paravertebral-unilateral | Chemotherapy | 14 | Mild kyphosis |