Skip to main content

View full-text article in PMC

. 2008 Mar 13;33(3):731–736. doi: 10.1007/s00264-008-0529-8

Table 2.

Chemotherapy agents and regimens used to treat LCH of the spine with obvious soft tissue extension in children

Agents	Dose	Regimens
Vincristine	0.5–1 mg/m²	IV, per week (3 months)
		IV, per two weeks (3 months)
		IV, per four weeks (3 months)
Methotrexate	5–10 mg/m²	IV, per week (3 months)
		IV, per two weeks (3 months)
		IV, per four weeks (3 months)
Prednisone	5 mg/m²	Oral, per day (9 months)
6-Mercaptopurine	10 mg/m²	Oral, per day (6 months)
6-Mercaptopurine	5 mg/m²	Oral, per day (3 months)

mg/m²=dose per body surface area; IV=intravenous