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Histological findings 24 weeks after surgery. Toluidine blue staining, original magnification ×20. a Untreated defect. b Defect treated with the gelatin sponge only (no E-rhBMP-2). c Defect treated with 1 μg E-rhBMP-2. d Defect treated with 5 μg E-rhBMP-2. e Defect treated with 40 μg rhBMP-2
