TABLE 1.
Medications Metabolized by CYP3A and CYP2E1
| CYP3A | CYP2E1 |
|---|---|
| Macrolide antibiotics | Anesthetics |
| Clarithromycin | Enflurane |
| Erythromycin | Halothane |
| Antiarrythmics | Isoflurane |
| Quinidine | Methoxyflurane |
| Benzodiazepines | Sevoflurane |
| Diazepam | Others |
| Midazolam | Acetaminophen |
| Immune modulators | Aniline |
| Cyclosporine | Benzene |
| Tacrolimus | Dacarbazine |
| HIV antivirals | Dapsone |
| Indinavir | Chlorzoxazone |
| Ritonavir | Ethanol |
| Saquinavir | Isoniazid |
| Antihistamines | N,N-dimethylformamide |
| Astemizole | Theophylline |
| Terfenadine | Toluene |
| Calcium channel blockers | Trimethadione |
| Felodipine | |
| Nifedipine | |
| Verapamil | |
| HMG CoA reductase inhibitors | |
| Atorvastatin | |
| Lovastatin | |
| Simvastatin | |
| Steroids | |
| Estradiol | |
| Hydrocortisone | |
| Progesterone | |
| Testosterone | |
| Other | |
| Caffeine | |
| Cocaine | |
| Codeine | |
| Dapsone | |
| Dexamethasone | |
| Dextromethorphan | |
| Fentanyl | |
| Gleevec | |
| Haloperidol | |
| Irinotecan | |
| Lidocaine | |
| Methadone | |
| Propranolol | |
| Quinine | |
| Risperidone | |
| Tamoxifen | |
| Taxol | |
| Terfenadine | |
| Vincristine |