TABLE 2.
Characteristics of Patients Studied Before and After Bariatric Surgery-Induced Weight Loss (n = 20)
| Preoperative | Postoperative | P | |
|---|---|---|---|
| Age (yr) | 43 ± 9 | NA | |
| Females/males | 12/8 | NA | |
| Time between biopsies (mo) | 15 ± 7 | NA | |
| BMI (kg/m2) | 54 ± 9 | 36 ± 9 | <0.001 |
| Fasting glucose (mg/dL) | 126 ± 34 | 97 ± 24 | 0.001 |
| AST (IU/L) | 30 ± 13 | 24 ± 9 | 0.059 |
| ALT (IU/L) | 43 ± 20 | 34 ± 12 | 0.044 |
| Lipids* | |||
| Total cholesterol (mg/dL) | 206 ± 52 | 178 ± 49 | 0.02 |
| Triglycerides (mg/dL) | 195 ± 92 | 117 ± 68 | <0.001 |
| HDL cholesterol (mg/dL) | 41 ± 14 | 44 ± 14 | 0.183 |
| LDL cholesterol (mg/dL) | 130 ± 39 | 116 ± 40 | 0.078 |
| Metabolic syndrome (%) | 12 (60) | 0 (0) | 0.001 |
| Hypertension (%) | 12 (60) | 2 (10) | 0.002 |
| Diabetes mellitus (%) | 7 (35) | 1 (5) | 0.014 |
| Insulin use (%) | 2 (10) | 1 (5) | 0.317 |
| Dyslipidemia (%) | 18 (90) | 5 (25) | <0.001 |
| Liver histology scores | |||
| Steatosis | 2.6 ± 0.7 | 0.7 ± 0.8 | <0.001 |
| Inflammation | 1.7 ± 0.7 | 0.9 ± 0.5 | 0.001 |
| Fibrosis | 1.6 ± 1.0 | 1.3 ± 1.0 | 0.035 |
| Disease grade | 2.2 ± 0.7 | 0.9 ± 0.4 | <0.001 |
| Disease stage | 1.7 ± 1.0 | 1.3 ± 1.0 | 0.011 |
Values are expressed as mean ± SD or n (%).
*
Excludes 2 patients missing postoperative lipid measures (n = 18).