Table 8.
Percent of oropharyngeal swallowing disorders observed in the 11 patients with laryngeal cancer treated with chemoradiation at pretreatment (baseline) and 3 and 12 mo posttreatment.
Baseline, % | Posttreatment | Overall p value by Cochran's Q | Pairwise p value by McNemar's | ||||
---|---|---|---|---|---|---|---|
3 mo, % | 12 mo, % | Baseline vs 3 mo | Baseline vs 12 mo | 3 vs 12 mo | |||
Description of disorder | |||||||
Reduced tongue base retraction | 55 | 82 | 91 | .039 | .08 | .05 | .32 |
Reduced tongue strength | 45 | 64 | 36 | .31 | .32 | .56 | .18 |
Delayed pharyngeal swallow | 36 | 45 | 36 | .85 | .56 | .99 | .56 |
Slowed/delayed vestibule closure | 18 | 55 | 55 | .14 | .10 | .05 | .99 |
Reduced tongue control | 27 | 27 | 36 | .78 | .99 | .56 | .56 |
Reduced A-P tongue movement | 0 | 45 | 64 | .008 | No test | No test | .32 |
Reduced laryngeal elevation | 36 | 55 | 55 | .51 | .32 | .32 | .99 |
Reduced tongue stabilization | 0 | 9 | 9 | .61 | No test | No test | .99 |
Bilateral pharyngeal weakness | 0 | 45 | 27 | .07 | No test | No test | .41 |
Reduced cricopharyngeal opening | 0 | 36 | 36 | .041 | No test | No test | .99 |
Visible cricopharyngeal bar | 9 | 0 | 9 | .61 | No test | .99 | No test |
Incomplete laryngeal vestibule closure | 9 | 18 | 18 | .72 | .32 | .56 | .99 |
Other measures of swallowing | |||||||
Functional swallow | 100 | 73 | 73 | No test | No test | No test | No test |
% Oral intake <50% | 0 | 36 | 18 | .050 | No test | No test | .16 |
% Normal diet | 55 | 18 | 45 | .16 | .10 | .65 | .083 |
Mean saliva weight (in grams) | 6.40 | 1.25 | 1.46 | <.001 | <.001 | <.001 | .74 |
SEM | 1.02 | 0.44 | 0.44 |
Abbreviations: SEM, standard error of the mean; A-P, anterior-posterior.
Note: Bolded values indicate p < .05 for overall test or p < .017 for pairwise test. (“No test” means frequencies were too low to perform statistical tests).