TABLE III.

Multivariate Relative Risks for Colon and Rectal Cancer from the Polytomous Logistic Regression Model with Corresponding p-Value for the Difference Between Colon and Rectal¹

	ENDPOINT		p for difference
	Colon	Rectum
Positive family history	1.94 (1.80, 2.10)	1.27 (1.08, 1.50)	0.02
Physical activity (per 5 MET increase)	0.90 (0.88, 0.93)	1.02 (0.98, 1.06)	0.02
Height (per 5 inches)	1.08 (1.05, 1.12)		0.07
Servings of processed meat (one additional serving per week)	1.20 (1.06, 1.37)		0.17
Female gender	0.59 (0.54, 0.63)		0.27
Servings of beef, pork or lamb (one additional serving per week)	1.12 (0.99, 1.27)		0.32
Total folate (per 100 mcg)	0.83 (0.70, 0.97)		0.45
Total calcium (per 100 mg)	0.76 (0.47, 1.25)		0.47
Pack-years of smoking before age 30 (per 5 pack years)	1.07 (1.05, 1.10)		0.61
BMI (per 5 unit increase in BMI)	1.06 (1.03, 1.10)		0.75
Alcohol (per 5 grams)	1.05 (1.03, 1.06)		0.76
Age (per 5 years)	1.21 (1.19, 1.23)		0.92

¹Model includes all of the above risk factors as well as history of endoscopy. Relative risks presented once were fixed to be equal for the 2 outcomes based on the stepwise approach to this analysis. See text for more detail.