TABLE 2.
Selection pressures acting on each lineage of chikungunya virus
Data set | Mean dN/dS (95% CI) |
I/Ea | No. of negatively selected codonsb | Positively selected codon positionb | ||
---|---|---|---|---|---|---|
Overall | Internal | External | ||||
Asian21 | 0.125 (0.108-0.142) | 0.095 (0.073-0.118) | 0.152 (0.125-0.179) | 0.63 | 70 | NA |
WAf11 | 0.066 (0.051-0.082) | 0.040 (0.016-0.063) | 0.075 (0.056-0.095) | 0.53 | 64 | NA |
ECSA9 | 0.088 (0.060-0.115) | 0.058 (0.049-0.068) | 0.103 (0.080-0.126) | 0.57 | 96 | NA |
Epidemic39 | 0.285 (0.232-0.338) | 0.278 (0.056-0.497) | 0.286 (0.300-0.343) | 0.97 | 16 | C-23; C-27; E1-226 |
I/E/, ration of internal to external values.
Significant at α = 0.05.