FIG. 1.

Overview of late domain mutations within RSV Gag. Established and putative late domain positions are in boldface type, and mutated amino acids are underlined. The PPPY and LYPSL sequences are located in the p2b and p10 domains of the Gag polyprotein, respectively. Mutants were constructed in the context of infectious RSV proviral DNA carrying a GFP reporter gene. LYPDL, PTAP, and FPIV are exogenous late domains used by EIAV, HIV-1, and the paramyxovirus SV5, respectively. MA, matrix; CA, capsid; SP, spacer; NC, nucleocapsid; PR, protease.