TABLE 1.
Relevant parameters of the patients enrolled
| Patient | Age in yr (sex) | Clinical diagnosisa | No. of CD34 cells grafted (106 cells/kg) | Survival (days) | TTV in plasma |
|||
|---|---|---|---|---|---|---|---|---|
| Pre-TBI |
Post-TBI |
|||||||
| No. of copies/ml | Genogroup(s) | No. of copies/mlb | Genogroup(s) | |||||
| 1 | 54 (male) | T-ALL | 23.60 | 30 | 6.8 | 1, 3, 5 | NDc | ND |
| 2 | 47 (female) | ALL | 9.41 | 174 | 4.7 | 1, 4 | 5.4 (day 80) | 1, 3, 4, 5 |
| 3 | 41 (female) | B-ALL | 11.70 | 111 | 5.3 | 1 | 4.2 (day 30) | 3 |
| 4 | 58 (female) | AML | 5.90 | 267 | 5.0 | 1 | 7.0 (day 110) | 1, 3, 4, 5 |
a
T-ALL, T-cell acute lymphoblastic leukemia; B-ALL, B-cell acute lymphoblastic leukemia; AML, acute myeloid leukemia.
b
The day post-TBI when TTV loads and genogroups were determined is shown in parentheses.
c
ND, not determined.