TABLE 2.
TTV dynamics in the patients enrolled
| Patient | Viral parameter |
||
|---|---|---|---|
| Clearance rate (c [days−1]) | Virion half-life (days)a | Minimal input and clearance of plasma virions/dayb | |
| 1 | 3.8 | 0.18 | 7.8 × 1010 |
| 2 | 4.5 | 0.15 | 6.7 × 109 |
| 3 | 3.7 | 0.19 | 2.1 × 109 |
| 4 | 3.5 | 0.20 | 9.6 × 108 |
| Mean ± SE | 3.8 ± 0.2 | 0.18 ± 0.01 | 2.0 × 1010 ± 1.0 × 1010 |
a
Calculated by the equation ln (2)/c.
b
Daily production of plasma virions was calculated from c multiplied by the pre-TBI viremia load value and by extracellular body fluid volume, which was arbitrarily set at 3.0 × 103 ml.