FIGURE 3.

Inhibition of OAT-PG-mediated [³H]PGE₂ uptake by various organic compounds. The OAT-PG-mediated uptake of [³H]PGE₂ (1 nm) was measured in the absence or presence of nonlabeled various organic compounds at 1 μm. The values were expressed as percent of the control [³H]PGE₂ uptake measured in the absence of the inhibitors (−). **, p < 0.01; ***, p < 0.001 (versus control [³H]PGE₂ uptake in the absence of inhibitors). PAH, para-aminohippurate; DHEAS, dehydroepiandrosterone sulfate; TEA, tetraethylammonium.