TABLE 1.
Kinetics parameters of OAT-PG substrates
Substrate | Kma | Vmaxa |
---|---|---|
nm | pmol/mg of protein/min | |
PGE2 | 118.3 ± 3.0 | 6.32 ± 0.05 |
PGF2α | 158.2 ± 18.7 | 4.61 ± 0.20 |
PGE1 | 156.8 ± 18.9 | 2.71 ± 0.11 |
PGD2 | 371.6 ± 58.1 | 8.95 ± 0.51 |
a Km and Vmax values were determined as described under “Experimental Procedures.” The table was constructed based on three separate experiments. Each value represents the mean ± S.E.