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SCD1 knockdown increases palmitic acid-induced UPR. At 48 h after siRNA transfection, cells were further incubated for 12 h in media supplemented with 16:0. The expression level of each gene was normalized to the GAPDH gene and is represented as -fold induction over untreated siControl. The data represent the mean ± S.E. of three experiments. The asterisks indicate significant differences compared with siControl-transfected cells (p < 0.01).
