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. 2010 Apr 30;285(29):22132–22140. doi: 10.1074/jbc.M110.120683

FIGURE 7.

FIGURE 7.

Analysis of the global MPB-activated Cl currents recorded for each CFTR mutant. A, I/V slope of current/voltage relationships. Dotted line corresponds to the wt level. B, upper, representatives time course of wt and S623A mutant in presence of 50 μm MPB-91. Lower, histograms representing the mean of time corresponding to 50% of activation for each mutant. ns, nonsignificant difference. ***, p < 0.001 compared with wt. Error bars, S.E.