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. 2010 May 4;285(29):22122–22131. doi: 10.1074/jbc.M110.107243

FIGURE 4.

FIGURE 4.

Inhibition of PBGS activity by active site-directed suicide inhibitors. Inhibition of TgPBGS and HsPBGS enzyme activity (under optimal conditions) by succinylacetone (A, preincubated 30 min) or 4,7-dioxosebacic acid (4,7-DOSA) (B, preincubated 100 min).