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. 2010 May 19;285(29):22291–22298. doi: 10.1074/jbc.M110.123794

FIGURE 1.

FIGURE 1.

Reduced LKB1 expression in endothelial cells isolated from Lkb1flox/+;Tie2Tg/+ (heterozygous LKB1-KO) mice. Upper, Western blot analysis for LKB1, Cre, and α-tubulin in endothelial cells isolated from lung of Lkb1flox/+;Tie2+/+, Lkb1flox/+;Tie2Tg/+, and Lkb1flox/flox;Tie2+/+ mice. Lower, histogram indicating LKB1 expression reproducible in isolated lung endothelial cells from Lkb1flox/+;Tie2Tg/+ mice (n = 6 in each group).