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Hypermetabolism protects Pemt−/− mice from HF diet-induced weight gain. All data are presented as means ± S.E. 8-week-old, male Pemt+/+ and Pemt−/− mice that had been fed the HFD diet (n = 8–10) for 8 weeks were acclimatized for 24 h in an Oxymax Lab Animal Monitoring System, and indirect calorimetry measurements were taken every 13 min over a 24-h period. A, oxygen consumption (p < 0.001). B, respiratory exchange ratio (RER) (p < 0.05).
