TABLE 3.
Peak exercise gas exchange and hemodynamic variables in controls and persons with T2DM.
| Controls (N = 10) | T2DM (N = 10) | |
|---|---|---|
| V̇O2peak (mL·kg−1·min−1) | 22.3 ± 4.2 | 18.7 ± 2.3* |
| V̇O2peak (mL·min−1) | 1639.9 ± 336.8 | 1519.8 ± 248.6 |
| RER | 1.14 ± 0.05 | 1.18 ± 0.05 |
| RPE | 17.1 ± 1.4 | 16.6 ± 1.8 |
| Watts | 123 ± 27.5 | 110 ± 21.1 |
| HR peak (beats·min−1) | 166 ± 15 | 169 ± 8 |
| CO (Fick) (L·min−1) | 13.5 ± 2.1 | 13.0 ± 1.9 |
| CI (Fick) (L·min−1·m−2) | 7.6 ± 1.1 | 7.1 ± 0.8 |
| CO (thermodilution) (L·min−1) | 16.2 ± 3.5 | 14.7 ± 2.3 |
| CI (thermodilution) (L·min−1·m−2) | 9.1 ± 1.6 | 7.9 ± 1.1 |
| Arteriovenous oxygen difference (vol.%) | 12.1 ± 1.4 | 11.8 ± 1.8 |
| SVR (dyn·s·cm−5) | 608 ± 112 | 668 ± 120 |
| LVSW (g·m−1) | 104 ± 24 | 101 ± 19 |
| MAP (mm Hg) | 107.6 ± 7.3 | 117.7 ± 12.6† |
| RAP (mm Hg) | 10.8 ± 3.1 | 10.7 ± 3.8 |
| Mean pulmonary arterial pressure (mm Hg) | 30.3 ± 6.7 | 34.0 ± 1.5 |
| PCWP (mm Hg) | 16.7 ± 3.7 | 23.6 ± 3.9‡ |
Data are given as mean ± SD.
Formula for calculating SVR is provided in the text.
*
P < 0.05, difference between controls and T2DM.
†
P = 0.06, difference between controls and T2DM.
‡
P < 0.01, difference between controls and T2DM.
CI, CO/body surface area; V̇O2peak, peak oxygen consumption.