Table 1.

Semi-quantitative scoring of fibrosis: a two-tired scoring system for histopathological liver changes after murine bile duct ligation

Periportal fibrosis	Score
No fibrosis	0
Scattered periportal and perineoductular fibrosis (incomplete lamellae)	1
Periportal, perineoductular fibrosis (complete lamellae) +/- beginning septa	2
Periportal, perineoductular fibrosis with portal-portal septa *	3
Complete cirrhosis	4
Perisinusoidal fibrosis
No fibrosis	0
Mild fibrosis (fibres in < 50% of the perisinusoidal spaces)	1
Severe fibrosis (fibres in > 50% of the perisinusoidal spaces)	2

*Three or more portal-portal septa have to be found per 10 portal fields.