Table 2.
Fibrosis index and semi-quantitative score
| Time after bile duct ligation (days) | Fibrosis index (%) | Semi-quantitative score | ||
|---|---|---|---|---|
| Portal fibrosis | Perisinusoidal fibrosis | Total score | ||
| 0 (n = 3) | 0.13 ± 0.04 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 |
| 3 (n = 5) | 0.10 ± 0.03 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 |
| 7 (n = 5) | 0.76 ± 0.11 | 0.60 ± 0.25 | 0.0 ± 0.0 | 0.60 ± 0.25 |
| 10 (n = 5) | 1.65 ± 0.22 | 1.40 ± 0.25 | 0.25 ± 0.25 | 1.67 ± 0.25 |
| 14 (n = 5) | 4.75 ± 0.35 | 2.4 ± 0.25 | 1.0 ± 0.0 | 3.40 ± 0.24 |
| 20 (n = 4) | 5.02 ± 0.47 | 3.0 ± 0.0 | 1.0 ± 0.0 | 4.0 ± 0.0 |
| 30 (n = 5) | 5.45 ± 0.35 | 2.8 ± 0.2 | 1.4 ± 0.25 | 4.20 ± 0.20 |
| 60 (n = 6) | 5.63 ± 0.25 | 3.0 ± 0.0 | 1.8 ± 0.17 | 4.83 ± 0.17 |
Fibrosis index (% Sirius Red stain) and semi-quantitative score consisting of portal fibrosis score, perisinusoidal score and total score (mean +/- standard error of mean; see Table 1)