Table 2.
Prevalence of individual symptoms of hypothyroidism at the time of diagnosis. (modified from: Alm et al. Brit Med J 289:1171-175, 1984 [13].)
| Features listed in questionnaire | Group 1 (n = 215) Initial T4 ≤ 30 nmol/L % with feature |
Group 2 (n = 232) Initial T4 > 30 nmol/L % with feature |
|---|---|---|
| Prolonged Jaundice | 59 | 33** |
| Feeding Difficulty | 35 | 16** |
| Lethargy | 34 | 14** |
| Umbilical Hernia | 32 | 18* |
| Macroglossia | 25 | 12* |
| Constipation | 18 | 10 |
| Cold or mottled skin | 18 | 10 |
| Hypothermia | 3 | 3 |
| No symptoms | 16 | 33** |
| Other clinical features reported: | ||
| Abnormal cry | 7 | 6 |
| Edema | 5 | 3 |
| Hypothyroid appearance | 6 | 2 |
| Hypotonia | 3 | 3 |
**p < 0.001, *p < 0.01.