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(A) Organization of the gene cluster surrounding the orsellinic acid synthase PKS (AN7907.4) in A. nidulans. Each arrow indicates the direction of transcription and the relative sizes of the ORFs deduced from analysis of the nucleotide sequences. ORFs AN7909.4 (PKS), AN7911.4 (decarboxylase) and AN7912.4 (tyrosinase) are involved in F-9775 A and B biosynthesis. (B) HPLC profile of extracts as detected by UV absorption at 254 nm.
