Table 1.
Plasma and liver lipids in running C57BL/6 mice compared with sedentary controls
| Sedentary (n = 6) | Running (n = 7) | |
|---|---|---|
| PLASMA LIPIDS | ||
| Total cholesterol (mg/dl) | 85 ± 3 | 78 ± 7 |
| HDL cholesterol (mg/dl) | 56 ± 5 | 49 ± 6 |
| Non-HDL cholesterol (mg/dl) | 29 ± 4 | 29 ± 6 |
| Triglycerides (mg/dl) | 68 ± 20 | 44 ± 16* |
| Phospholipids (mg/dl) | 182 ± 7 | 155 ± 23 |
| MORPHOLOGICAL DATA | ||
| Body weight (g) | 22.2 ± 1.1 | 21.8 ± 1.3 |
| Liver weight (g) | 0.98 ± 0.06 | 1.1 ± 0.06** |
| Liver weight (% of body weight) | 4.4 ± 0.2 | 5.0 ± 0.3** |
| Food intake (g/d) | 4.1 ± 0.3 | 5.4 ± 0.5*** |
| LIVER LIPIDS | ||
| Total cholesterol (μmol/g) | 7.3 ± 0.8 | 6.3 ± 0.7 |
| Free cholesterol (μmol/g) | 6.6 ± 0.8 | 5.6 ± 0.7* |
| Cholesterol esters (μmol/g) | 0.7 ± 0.3 | 0.6 ± 0.1 |
| Triglycerides (μmol/g) | 24.3 ± 3.6 | 14.0 ± 2.3*** |
| Phospholipids (μmol/g) | 37.8 ± 5.5 | 33.3 ± 5.3 |
Values are means ± SD determined after 2 weeks of voluntary wheel running exercise. Significant differences from sedentary mice are indicated as: * p < 0.05; ** p < 0.01; *** p < 0.001.