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Effect of c-erbB2 siRNA, PD98059 and calphostin on the initiation of primordial follicle growth. (A), Ovaries were cultured for 8 days with treatments: A, control; B, 0.1 mmol/L siRNA; C, 5 × 10-2 mmol/L PD98059; D, 5 × 10-4 mmol/L calphostin. (B), The number of follicles was counted in serial cross-sections. Percentage of the number of each category over the total number was plotted. Data are presented as means ± SEM (n = 5) **, P < 0.01 vs control.
