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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Glia. 2010 Jun;58(8):932–942. doi: 10.1002/glia.20975

FIGURE 1.

FIGURE 1

SRC-3−/− mice are lean with increased lipid metabolism rate compared to SRC-3+/+ mice. (A) Body weight of SRC-3+/+ (n=17) and SRC-3−/− mice (n=16). * P < 0.05. (B) Mice were maintained on a high-fat diet for 2 months, representative triglyceride accumulation in livers (×200) and heart muscles (×100) from SRC-3+/+ and SRC-3−/− mice were indicated by Oil-Red O staining. (C) Quantification of mRNA expression of SCD1, FAS, ACC1, Cpt1 and Acad in livers from high-fat diet-fed SRC-3+/+ (solid bars) and SRC-3−/− (open bars).