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. Author manuscript; available in PMC: 2011 Aug 15.
Published in final edited form as: Free Radic Biol Med. 2010 Jun 2;49(4):567–579. doi: 10.1016/j.freeradbiomed.2010.04.037

Fig. 7.

Fig. 7

IsoKs accelerate cytochrome c release from liver mitochondria. A. Changes in the absorbance of a mitochondrial suspension treated with Ca2+, either in the absence (line 1) or presence of IsoKs (0.5–4 μM), (lines 2–5). Samples (50 μL) were taken every 3 min before or after Ca2+ addition. Cytochrome c concentration was measured by immunoassay kit. B. Dependence of the time of maximum cytochrome c release on the presence of IsoKs. C. Cytochrome c was released into the medium after the addition of Ca2+ and IsoKs. D. Relationship between the concentration of cytochrome c released into the medium and mitochondrial swelling. Data were plotted as the mean ± sem, N=3, *, p < 0.05 compare with IsoKs untreated mitochondria.