Fig. 9.
Addition of exogenous cytochrome c restores mitochondrial respiration affected by IsoKs and Ca2+. Line 1 represents mitochondrial respiration measured in the presence of Ca2+ (20 μM), line 2 – in the presence of IsoKs (4 μM) and Ca2+, line 3 - in the presence of IsoKs (4 μM) and Ca2+ and exogenously added cytochrome c (10 μM). Experimental conditions were the same as on Fig. 1. Representative traces from 3 experiments are shown.