5-HT1A Receptor-regulated Signal Transduction Pathways.
5-HT, serotonin; 5-HT1A, serotonin 1A receptors; Gi, inhibitory Guanine nucleotide binding protein; AC, adenylyl cyclase; cAMP, cyclic adenosine monophosphate; GIRK, G-protein coupled inward rectifying potassium channel; GFR, growth factor receptor; PKA, protein kinase A; CREB, cAMP response element binding protein; MEK1/2, MAP and ERK kinase 1/2; ERK 1/2, extracellular signal-regulated kinase 1/2; RSK, ribosomal S6 kinase; PI3K, phosphotidylinositol-3 kinase; PDK, phosphoinositide dependent kinase; GSK3, glycogen synthase kinase-3; FoxO, forkhead box O transcription factors