Effect of UK 14,304 on NE oxidation currents and neurogenic constrictions. (A) NE oxidation currents recorded in the presence of UK 14,304 (1 μM) in sham and DOCA-salt MA. (B) NE oxidation currents recorded in the presence of UK 14,304 in sham and DOCA-salt MV. Data are expressed as % of the response obtained in each tissue before UK 14,304 application. * Indicates a significant decrease below control levels (100%, P< 0.05). # Indicates significantly different from the levels in DOCA-salt MA (P< 0.05). Frequency–response curves for neurogenic constrictions in sham and DOCA-salt MA (B) and sham and DOCA-salt MV (D) in the absence and presence of UK 14,304. Data are mean ±S.E.M.