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. 2010 Jan-Feb;1(1):19–28. doi: 10.4161/viru.1.1.9868

Figure 5.

Figure 5

Relationship between Tax mRNA level, proviral load and spontaneous NK cell proliferation. (A) The Tax score to quantify Tax mRNA expression was calculated as in Figure 4 and compared in subjects with HAM/TSP (n = 6) and HTLV-1 carriers (n = 12), with HAM/TSP subjects showing higher Tax scores from PBMCs after 7 days' in vitro culture. (B) proliferation of CD8+ T cells at day 7 (%CFSElow) was compared to Tax expression at day 7 in HTLV-1 infected subjects (n = 13) and analyzed by linear regression. (C) proviral load was measured in ex vivo PBMCs in subjects with HAM/TSP (n = 6) and HTLV-1 carriers (n = 15). (D) Proliferation of CD8+ T cells at day 7 (%CFSElow) was compared to HTLV-1 proviral load ex vivo in HTLV-1 infected subjects (n = 15) and analyzed by linear regression.