Table 2.
YAL Sal (n = 7) | YAL IL (n = 6) | OCR Sal (n = 5) | OCR IL (n = 5) | OAL Sal (n = 5) | OAL IL (n = 6) | |
Clamp FFA (meq/L) | 0.11 ± 0.04 | 2.06 ± 0.26* | 0.33 ± 0.05 | 1.94 ± 0.47* | 0.86 ± 0.25 | 1.86 ± 0.12* |
Clamp glucose (mmol/L) | 6.71 ± 0.10 | 6.38 ± 0.11 | 6.61 ± 0.22 | 6.61 ± 0.05 | 8.13 ± 0.06 | 7.52 ± 0.22 |
Clamp insulin (ng/mL) | 3.96 ± 0.33 | 4.18 ± 0.11 | 4.67 ± 0.44 | 4.64 ± 0.08 | 6.23 ± 0.96 | 6.49 ± 0.82 |
Notes: YAL, OAL, and OCR rats underwent 5 hours of saline (Sal) or IL infusion during a hyperinsulinemic–euglycemic clamp. The average plasma FFA, glucose, and insulin levels (clamp) over the last hour are shown. Data are means ± SE. FFA = free fatty acids; IL = intralipid.
Significant effect of treatment within group, p < .05.