TABLE 2.

VLDL, IDL, and LDL apoB kinetic parameters

	Subject Group			P
Parameter	E2/E2-N	E2/E2-H	E3/E2-H	E2/E2-N vs. E2/E2-H	E2/E2-N vs. E3/E2-H	E2/E2-H vs. E3/E2-H
ApoB concentrations (mg/dl)
VLDL	4.01 ± 0.39	18.3 ± 3.76	18.3 ± 5.81	0.005	0.012	0.998
IDL	5.10 ± 1.17	14.8 ± 3.05	7.73 ± 0.91	0.016	0.093	0.040
LDL	28.0 ± 6.08	38.3 ± 6.56	84.6 ± 18.4	0.316	0.019	0.026
FCR (pools/day)
VLDL	2.57 ± 0.47	1.13 ± 0.20	1.52 ± 0.17	0.022	0.044	0.175
IDL	1.15 ± 0.20	0.67 ± 0.11	0.83 ± 0.08	0.059	0.118	0.275
LDL	0.70 ± 0.07	0.41 ± 0.06	0.38 ± 0.09	0.025	0.040	0.762
PR (mg/kg/day)
VLDL	4.78 ± 1.18	8.24 ± 1.29	11.5 ± 2.51	0.102	0.073	0.372
IDL	2.78 ± 1.03	3.73 ± 0.30	2.83 ± 0.37	0.201	0.701	0.075
LDL	8.88 ± 1.94	6.73 ± 1.03	12.8 ± 2.33	0.386	0.288	0.036
Conversion rate (%)
VLDL to IDL	65.6 ± 22.1	47.7 ± 4.26	31.2 ± 8,58	0.504	0.132	0.123
IDL to LDL	43.8 ± 8.25	50.3 ± 4.52	80.1 ± 7.80	0.473	0.021	0.009
VLDL to LDL	28.4 ± 11.7	23.3 ± 0.50	23.6 ± 5.03	0.702	0.672	0.949
VLDL apoB in slowly turning over  compartment (%)	9.80 ± 1.86	26.0 ± 2.95	7.69 ± 2.75	0.008	0.609	0.002
Direct LDL synthesis (%)	85.8 ± 5.23	70.3 ± 3.72	80.2 ± 4.08	0.047	0.427	0.111

Data presented as mean ± SEM. Bold text indicates statistical significance a P < 0.05. N: normolipidemic; H: hyperlipidemic.