Fig. 8.

Bright field microscopy images of hematoxylin-eosin-stained sections of ovaries from WT (A, C) or SCARB1^−/− mature mice stimulated with eCG and hCG and collected 18 h after hCG. Mice received placebo injections (A, B) or a combination of 20 µg/g BW mevinolin (Mev; an HMGR inhibitor) and 100 µg/g BW chloroquine (Chloro; an inhibitor of lysosomal processing of LDL) (C, D). Bars: 200 µm. CL, corpus luteum; eCG, equine chorionic gonadotropin; F, follicle; hCG, human chorionic gonadotropin; HMGR, 3-hydroxy-3-methylglutaryl CoA reductase; SCARB1, scavenger receptor-B1; WT, wild type.